Gold Key's The Man from U.N.C.L.E. #3 (Novemberr 1965) was written by Dave Wood, with art by George Tuska for the first 26 pages and (for reasons I imagine are lost to the ages) Dan Heck stepping in to draw the last 6 pages.
I tried three times to write up a summary of this story. Each time, the convolutions and lightening fast pace foiled my attempts to concisely summarize it at all. This isn't a criticism of the story--the twists and turns of the plot are part of what makes it a delight to read.
The bare bones summary is that THRUSH is trying to find the secret lab where a scientist is cranking out secret weapons for U.N.C.L.E in the forms of toys and novelty items.
Starting with this premise, this comic book succeeds in exactly the same way the early seasons of the TV series succeeded. The story can be enjoyed as an espionage thriller, but can also be appreciated as a parody of that genre.
Specifically, it was making fun of the many, increasingly wild gadgets that were becoming a staple of the James Bond films. This began with From Russia, With Love (1963) but really went into high gear with Bond's Aston Martin in Goldfinger (1964).